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FITs: forest of imputation trees for recovering true signals in single-cell open chromatin profiles
The advent of single-cell open-chromatin profiling technology has facilitated the analysis of heterogeneity of activity of regulatory regions at single-cell resolution. However, stochasticity and availability of low amount of relevant DNA, cause high drop-out rate and noise in single-cell open-chrom...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676476/ https://www.ncbi.nlm.nih.gov/pubmed/33575635 http://dx.doi.org/10.1093/nargab/lqaa091 |