Single-cell lineage mapping of a diverse virus-specific naive CD4 T cell repertoire

Tracking how individual naive T cells from a natural TCR repertoire clonally expand, differentiate, and make lineage choices in response to an infection has not previously been possible. Here, using single-cell sequencing technology to identify clones by their unique TCR sequences, we were able to t...

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Detalles Bibliográficos
Autores principales: Khatun, Achia, Kasmani, Moujtaba Y., Zander, Ryan, Schauder, David M., Snook, Jeremy P., Shen, Jian, Wu, Xiaopeng, Burns, Robert, Chen, Yi-Guang, Lin, Chien-Wei, Williams, Matthew A., Cui, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676493/
https://www.ncbi.nlm.nih.gov/pubmed/33201171
http://dx.doi.org/10.1084/jem.20200650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676493/
https://www.ncbi.nlm.nih.gov/pubmed/33201171
http://dx.doi.org/10.1084/jem.20200650

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