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In silico and in vitro studies on the anti-cancer activity of andrographolide targeting survivin in human breast cancer stem cells

Breast cancer stem cells (BCSCs) express high levels of the anti-apoptotic protein, survivin. This study aimed to discover a natural active compound with anti-cancer properties that targeted survivin in human breast cancer stem cells. From the seven examined compounds, andrographolide was selected a...

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Detalles Bibliográficos
Autores principales: Wanandi, Septelia Inawati, Limanto, Agus, Yunita, Elvira, Syahrani, Resda Akhra, Louisa, Melva, Wibowo, Agung Eru, Arumsari, Sekar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676700/
https://www.ncbi.nlm.nih.gov/pubmed/33211707
http://dx.doi.org/10.1371/journal.pone.0240020