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In silico and in vitro studies on the anti-cancer activity of andrographolide targeting survivin in human breast cancer stem cells
Breast cancer stem cells (BCSCs) express high levels of the anti-apoptotic protein, survivin. This study aimed to discover a natural active compound with anti-cancer properties that targeted survivin in human breast cancer stem cells. From the seven examined compounds, andrographolide was selected a...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676700/ https://www.ncbi.nlm.nih.gov/pubmed/33211707 http://dx.doi.org/10.1371/journal.pone.0240020 |