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Guanosine Tetraphosphate Has a Similar Affinity for Each of Its Two Binding Sites on Escherichia coli RNA Polymerase

During nutrient deprivation, the bacterial cell undergoes a stress response known as the stringent response. This response is characterized by induction of the nucleotide derivative guanosine tetraphosphate (ppGpp) that dramatically modulates the cell’s transcriptome. In Escherichia coli, ppGpp regu...

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Detalles Bibliográficos
Autores principales: Myers, Angela R., Thistle, Danielle P., Ross, Wilma, Gourse, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676912/
https://www.ncbi.nlm.nih.gov/pubmed/33250875
http://dx.doi.org/10.3389/fmicb.2020.587098