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Guanosine Tetraphosphate Has a Similar Affinity for Each of Its Two Binding Sites on Escherichia coli RNA Polymerase
During nutrient deprivation, the bacterial cell undergoes a stress response known as the stringent response. This response is characterized by induction of the nucleotide derivative guanosine tetraphosphate (ppGpp) that dramatically modulates the cell’s transcriptome. In Escherichia coli, ppGpp regu...
Autores principales: | Myers, Angela R., Thistle, Danielle P., Ross, Wilma, Gourse, Richard L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7676912/ https://www.ncbi.nlm.nih.gov/pubmed/33250875 http://dx.doi.org/10.3389/fmicb.2020.587098 |
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