Identification of Spacer and Protospacer Sequence Requirements in the Vibrio cholerae Type I-E CRISPR/Cas System

The prokaryotic adaptive immune system CRISPR/Cas serves as a defense against bacteriophage and invasive nucleic acids. A type I-E CRISPR/Cas system has been detected in classical biotype isolates of Vibrio cholerae, the causative agent of the disease cholera. Experimental characterization of this s...

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Detalles Bibliográficos
Autores principales: Bourgeois, Jacob, Lazinski, David W., Camilli, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677007/
https://www.ncbi.nlm.nih.gov/pubmed/33208517
http://dx.doi.org/10.1128/mSphere.00813-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677007/
https://www.ncbi.nlm.nih.gov/pubmed/33208517
http://dx.doi.org/10.1128/mSphere.00813-20

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