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Backcrossing to an appropriate genetic background improves the birth rate of carbohydrate sulfotransferase 14 gene-deleted mice

Ehlers–Danlos syndromes (EDSs) are heterogeneous group of heritable connective tissue disorders characterized by joint and skin hyperextensibility as well as fragility of various organs. Recently, we described a new type of EDS, musculocontractual EDS (mcEDS-CHST14), caused by pathogenic variants of...

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Detalles Bibliográficos
Autores principales: Shimada, Shin, Yoshizawa, Takahiro, Takahashi, Yuki, Nitahara-Kasahara, Yuko, Okada, Takashi, Nomura, Yoshihiro, Yamanaka, Hitoki, Kosho, Tomoki, Matsumoto, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677086/
https://www.ncbi.nlm.nih.gov/pubmed/32522905
http://dx.doi.org/10.1538/expanim.19-0150