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Recombinant Treponema pallidum protein Tp0768 promotes proinflammatory cytokine secretion of macrophages through ER stress and ROS/NF-κB pathway

ABSTRACT: In response to danger signals, macrophages rapidly produce many inflammatory cytokines that trigger the cascade release of inflammatory mediators, leading to tissue damage, which is an important cause of clinical manifestations of syphilis at all stages. However, we still know very little...

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Detalles Bibliográficos
Autores principales: Li, Wei, Zhou, Xiangping, Cai, Jialun, Zhao, Feijun, Cao, Ting, Ning, Lichang, Luo, Chunyi, Xiao, Xinhua, Liu, Shuangquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677105/
https://www.ncbi.nlm.nih.gov/pubmed/33216161
http://dx.doi.org/10.1007/s00253-020-11018-8