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How Ancestry Influences the Chances of Finding Unrelated Donors: An Investigation in Admixed Brazilians
A match of HLA loci between patients and donors is critical for successful hematopoietic stem cell transplantation. However, the extreme polymorphism of HLA loci – an outcome of millions of years of natural selection – reduces the chances that two individuals will carry identical combinations of mul...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677137/ https://www.ncbi.nlm.nih.gov/pubmed/33240273 http://dx.doi.org/10.3389/fimmu.2020.584950 |