How Ancestry Influences the Chances of Finding Unrelated Donors: An Investigation in Admixed Brazilians

A match of HLA loci between patients and donors is critical for successful hematopoietic stem cell transplantation. However, the extreme polymorphism of HLA loci – an outcome of millions of years of natural selection – reduces the chances that two individuals will carry identical combinations of mul...

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Detalles Bibliográficos
Autores principales: Nunes, Kelly, Aguiar, Vitor R. C., Silva, Márcio, Sena, Alexandre C., de Oliveira, Danielli C. M., Dinardo, Carla L., Kehdy, Fernanda S. G., Tarazona-Santos, Eduardo, Rocha, Vanderson G., Carneiro-Proietti, Anna Barbara F., Loureiro, Paula, Flor-Park, Miriam V., Maximo, Claudia, Kelly, Shannon, Custer, Brian, Weir, Bruce S., Sabino, Ester C., Porto, Luís Cristóvão, Meyer, Diogo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677137/
https://www.ncbi.nlm.nih.gov/pubmed/33240273
http://dx.doi.org/10.3389/fimmu.2020.584950

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