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Structural Modeling and Molecular Dynamics of the Immune Checkpoint Molecule HLA-G

HLA-G is considered to be an immune checkpoint molecule, a function that is closely linked to the structure and dynamics of the different HLA-G isoforms. Unfortunately, little is known about the structure and dynamics of these isoforms. For instance, there are only seven crystal structures of HLA-G...

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Detalles Bibliográficos
Autores principales: Arns, Thais, Antunes, Dinler A., Abella, Jayvee R., Rigo, Maurício M., Kavraki, Lydia E., Giuliatti, Silvana, Donadi, Eduardo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677236/
https://www.ncbi.nlm.nih.gov/pubmed/33240264
http://dx.doi.org/10.3389/fimmu.2020.575076