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Loss of the spectraplakin gene Short stop induces a DNA damage response in Drosophila epithelia
Epithelia are an eminent tissue type and a common driver of tumorigenesis, requiring continual precision in cell division to maintain tissue structure and genome integrity. Mitotic defects often trigger apoptosis, impairing cell viability as a tradeoff for tumor suppression. Identifying conditions t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677407/ https://www.ncbi.nlm.nih.gov/pubmed/33214581 http://dx.doi.org/10.1038/s41598-020-77159-y |