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Antioxidant or pro-oxidant and glutathione transferase P1-1 inhibiting activities for Tamarindus indica seeds and their cytotoxic effect on MCF-7 cancer cell line

BACKGROUND: The multidrug resistance (MDR) of cancer cells is a major obstacle to cancer treatment. Glutathione S-transferase Pi (GSTP1-1) catalyzes the conjugation of glutathione with anticancer drugs and therefore reduces their efficacy. Phenolic compounds have the potential to inhibit GST P1-1 ac...

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Detalles Bibliográficos
Autores principales: Guneidy, R. A., Gad, A. M., Zaki, E. R., Ibrahim, F. M., Shokeer, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677421/
https://www.ncbi.nlm.nih.gov/pubmed/33215267
http://dx.doi.org/10.1186/s43141-020-00077-z