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TRIM24-RIP3 axis perturbation accelerates osteoarthritis pathogenesis

OBJECTIVES: Recently, necroptosis has attracted increasing attention in arthritis research; however, it remains unclear whether its regulation is involved in osteoarthritis (OA) pathogenesis. Since receptor-interacting protein kinase-3 (RIP3) plays a pivotal role in necroptosis and its dysregulation...

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Detalles Bibliográficos
Autores principales: Jeon, Jimin, Noh, Hyun-Jin, Lee, Hyemi, Park, Han-Hee, Ha, Yu-Jin, Park, Seok Hee, Lee, Haeseung, Kim, Seok-Jung, Kang, Ho Chul, Eyun, Seong-il, Yang, Siyoung, Kim, You-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677493/
https://www.ncbi.nlm.nih.gov/pubmed/32895234
http://dx.doi.org/10.1136/annrheumdis-2020-217904