RNaseH-mediated simultaneous piggyback knockdown of multiple genes in adult zebrafish

We recently developed a piggyback knockdown method that was used to knockdown genes in adult zebrafish. In this method, a vivo morpholino (VMO) piggybacks an antisense deoxyoligonucleotide (dO) into the somatic cells and reduces the cognate mRNA levels. In this paper, we tested whether we can piggyb...

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Detalles Bibliográficos
Autores principales: Raman, Revathi, Ryon, Mia, Jagadeeswaran, Pudur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677540/
https://www.ncbi.nlm.nih.gov/pubmed/33214638
http://dx.doi.org/10.1038/s41598-020-76655-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677540/
https://www.ncbi.nlm.nih.gov/pubmed/33214638
http://dx.doi.org/10.1038/s41598-020-76655-5

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