In situ ophthalmic gel forming systems of poloxamer 407 and hydroxypropyl methyl cellulose mixtures for sustained ocular delivery of chloramphenicole: optimization study by factorial design

BACKGROUND: Conventional drug delivery systems have some major drawbacks such as low bioavailability, short residence time and rapid precorneal drainage. An in situ gel drug delivery system provides several benefits, such as prolonged pharmacological duration of action, simpler production techniques...

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Detalles Bibliográficos
Autores principales: Kurniawansyah, Insan Sunan, Rusdiana, Taofik, Sopyan, Iyan, Ramoko, Handrian, Wahab, Habibah A., Subarnas, Anas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677690/
https://www.ncbi.nlm.nih.gov/pubmed/33251348
http://dx.doi.org/10.1016/j.heliyon.2020.e05365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677690/
https://www.ncbi.nlm.nih.gov/pubmed/33251348
http://dx.doi.org/10.1016/j.heliyon.2020.e05365

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