The Nrf2 induction prevents ferroptosis in Friedreich's Ataxia

Ferroptosis is an iron-dependent cell death caused by impaired glutathione metabolism, lipid peroxidation and mitochondrial failure. Emerging evidences report a role for ferroptosis in Friedreich's Ataxia (FRDA), a neurodegenerative disease caused by the decreased expression of the mitochondria...

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Detalles Bibliográficos
Autores principales: La Rosa, Piergiorgio, Petrillo, Sara, Turchi, Riccardo, Berardinelli, Francesco, Schirinzi, Tommaso, Vasco, Gessica, Lettieri-Barbato, Daniele, Fiorenza, Maria Teresa, Bertini, Enrico S., Aquilano, Katia, Piemonte, Fiorella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677700/
https://www.ncbi.nlm.nih.gov/pubmed/33197769
http://dx.doi.org/10.1016/j.redox.2020.101791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677700/
https://www.ncbi.nlm.nih.gov/pubmed/33197769
http://dx.doi.org/10.1016/j.redox.2020.101791

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