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Kinetic Separation of Oxidative and Non-oxidative Metabolism in Single Phagosomes from Alveolar Macrophages: Impact on Bacterial Killing

The relative contribution of the two phagosomal catabolic processes, oxidative and metabolic, was assessed in the killing of Pseudomonas aeruginosa in phagosomes of alveolar macrophages (AMs) from wild-type (p47-phox(+/+)) or NOX-defective (p47-phox(−/−)) mice. Free radical release and degradative a...

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Detalles Bibliográficos
Autores principales: Riazanski, Vladimir, Sui, Zihao, Nelson, Deborah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677711/
https://www.ncbi.nlm.nih.gov/pubmed/33251491
http://dx.doi.org/10.1016/j.isci.2020.101759