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I-Impute: a self-consistent method to impute single cell RNA sequencing data

BACKGROUND: Single-cell RNA-sequencing (scRNA-seq) is becoming indispensable in the study of cell-specific transcriptomes. However, in scRNA-seq techniques, only a small fraction of the genes are captured due to “dropout” events. These dropout events require intensive treatment when analyzing scRNA-...

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Detalles Bibliográficos
Autores principales: Feng, Xikang, Chen, Lingxi, Wang, Zishuai, Li, Shuai Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677776/
https://www.ncbi.nlm.nih.gov/pubmed/33208097
http://dx.doi.org/10.1186/s12864-020-07007-w