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Prospective randomized trial comparing efficacy and safety of intravenous and intra-articular tranexamic acid in total knee arthroplasty

BACKGROUND: Total knee arthroplasty (TKA) is associated with significant perioperative blood loss and postoperative allogenic blood transfusion. Tranexamic acid (TXA) reversibly blocks lysine binding sites on plasminogen molecules and inhibits plasmin formation. Comparisons of the efficacy and safet...

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Detalles Bibliográficos
Autores principales: Li, Moses Man-Lung, Kwok, Jojo Yan-Yan, Chung, Kwong-Yin, Cheung, Kin-Wing, Chiu, Kwok-Hing, Chau, Wai-Wang, Ho, Kevin Ki-Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677817/
https://www.ncbi.nlm.nih.gov/pubmed/33208180
http://dx.doi.org/10.1186/s43019-020-00079-8