Cargando…

The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

BACKGROUND: Duchenne muscular dystrophy (DMD) is a progressive, degenerative muscular disorder and cognitive dysfunction caused by mutations in the dystrophin gene. It is characterized by excess inflammatory responses in the muscle and repeated degeneration and regeneration cycles. Neutral sphingomy...

Descripción completa

Detalles Bibliográficos
Autores principales: Matsuzaka, Yasunari, Tanihata, Jun, Ooshima, Yoshiko, Yamada, Daisuke, Sekiguchi, Masayuki, Miyatake, Shouta, Aoki, Yoshitsugu, Terumitsu, Mika, Yashiro, Ryu, Komaki, Hirofumi, Ishiyama, Akihiko, Oya, Yasushi, Inoue, Yukiko U., Inoue, Takayoshi, Takeda, Shin’ichi, Hashido, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677854/
https://www.ncbi.nlm.nih.gov/pubmed/33208172
http://dx.doi.org/10.1186/s12916-020-01805-5