Therapeutic targeting of FLT3 and associated drug resistance in acute myeloid leukemia

Acute myeloid leukemia (AML) is a heterogeneous disease caused by several gene mutations and cytogenetic abnormalities affecting differentiation and proliferation of myeloid lineage cells. FLT3 is a receptor tyrosine kinase commonly overexpressed or mutated, and its mutations are associated with poo...

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Detalles Bibliográficos
Autores principales: Gebru, Melat T., Wang, Hong-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678146/
https://www.ncbi.nlm.nih.gov/pubmed/33213500
http://dx.doi.org/10.1186/s13045-020-00992-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678146/
https://www.ncbi.nlm.nih.gov/pubmed/33213500
http://dx.doi.org/10.1186/s13045-020-00992-1

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