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Therapeutic targeting of FLT3 and associated drug resistance in acute myeloid leukemia
Acute myeloid leukemia (AML) is a heterogeneous disease caused by several gene mutations and cytogenetic abnormalities affecting differentiation and proliferation of myeloid lineage cells. FLT3 is a receptor tyrosine kinase commonly overexpressed or mutated, and its mutations are associated with poo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678146/ https://www.ncbi.nlm.nih.gov/pubmed/33213500 http://dx.doi.org/10.1186/s13045-020-00992-1 |