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Construction of a Mex3c Gene-Deficient Mouse Model to Study C-FOS Expression in Hypothalamic Nuclei and Observe Morphological Differences in Embryonic Neural Tube Development

BACKGROUND: This study utilized CRISPR/Cas9 gene editing technology to construct a Mex3c gene-deficient mouse model, and studied C-FOS expression in hypothalamic nuclei. MATERIAL/METHODS: Thirty Mex3c(−/+) mice, 30 mice in the normal group, and 30 Mex3c(−/+) mice were randomly divided into control,...

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Detalles Bibliográficos
Autores principales: Du, Yong, Huo, Quan, Li, Ting, Sun, Dongjun, Sun, Ting, Lu, Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678243/
https://www.ncbi.nlm.nih.gov/pubmed/33191393
http://dx.doi.org/10.12659/MSM.927334