Cargando…

Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia

Epigenetic regulation of gene expression occurs in a cell type-specific manner. Current cell-type specific neuroepigenetic studies rely on cell sorting methods that can alter cell phenotype and introduce potential confounds. Here we demonstrate and validate a Nuclear Tagging and Translating Ribosome...

Descripción completa

Detalles Bibliográficos
Autores principales: Chucair-Elliott, Ana J., Ocañas, Sarah R., Stanford, David R., Ansere, Victor A., Buettner, Kyla B., Porter, Hunter, Eliason, Nicole L., Reid, Justin J., Sharpe, Amanda L., Stout, Michael B., Beckstead, Michael J., Miller, Benjamin F., Richardson, Arlan, Freeman, Willard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678837/
https://www.ncbi.nlm.nih.gov/pubmed/33214681
http://dx.doi.org/10.1038/s42003-020-01418-x