Cargando…
Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia
Epigenetic regulation of gene expression occurs in a cell type-specific manner. Current cell-type specific neuroepigenetic studies rely on cell sorting methods that can alter cell phenotype and introduce potential confounds. Here we demonstrate and validate a Nuclear Tagging and Translating Ribosome...
Autores principales: | Chucair-Elliott, Ana J., Ocañas, Sarah R., Stanford, David R., Ansere, Victor A., Buettner, Kyla B., Porter, Hunter, Eliason, Nicole L., Reid, Justin J., Sharpe, Amanda L., Stout, Michael B., Beckstead, Michael J., Miller, Benjamin F., Richardson, Arlan, Freeman, Willard M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678837/ https://www.ncbi.nlm.nih.gov/pubmed/33214681 http://dx.doi.org/10.1038/s42003-020-01418-x |
Ejemplares similares
-
Microglial MHC-I induction with aging and Alzheimer’s is conserved in mouse models and humans
por: Kellogg, Collyn M., et al.
Publicado: (2023) -
Differential usage of DNA modifications in neurons, astrocytes, and microglia
por: Tooley, Kyla B., et al.
Publicado: (2023) -
Differential Regulation of Mouse Hippocampal Gene Expression Sex Differences by Chromosomal Content and Gonadal Sex
por: Ocañas, Sarah R., et al.
Publicado: (2022) -
Specificity and efficiency of tamoxifen-mediated Cre induction is equivalent regardless of age
por: Kellogg, Collyn M., et al.
Publicado: (2023) -
Minimizing the Ex Vivo Confounds of Cell-Isolation Techniques on Transcriptomic and Translatomic Profiles of Purified Microglia
por: Ocañas, Sarah R., et al.
Publicado: (2022)