NQO1 protects obese mice through improvements in glucose and lipid metabolism

Chronic nutrient excess leads to metabolic disorders and insulin resistance. Activation of stress-responsive pathways via Nrf2 activation contributes to energy metabolism regulation. Here, inducible activation of Nrf2 in mice and transgenesis of the Nrf2 target, NQO1, conferred protection from diet-...

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Detalles Bibliográficos
Autores principales: Di Francesco, Andrea, Choi, Youngshim, Bernier, Michel, Zhang, Yingchun, Diaz-Ruiz, Alberto, Aon, Miguel A., Kalafut, Krystle, Ehrlich, Margaux R., Murt, Kelsey, Ali, Ahmed, Pearson, Kevin J., Levan, Sophie, Preston, Joshua D., Martin-Montalvo, Alejandro, Martindale, Jennifer L., Abdelmohsen, Kotb, Michel, Cole R., Willmes, Diana M., Henke, Christine, Navas, Placido, Villalba, Jose Manuel, Siegel, David, Gorospe, Myriam, Fritz, Kristofer, Biswal, Shyam, Ross, David, de Cabo, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678866/
https://www.ncbi.nlm.nih.gov/pubmed/33298924
http://dx.doi.org/10.1038/s41514-020-00051-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678866/
https://www.ncbi.nlm.nih.gov/pubmed/33298924
http://dx.doi.org/10.1038/s41514-020-00051-6

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