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Glucokinase intrinsically regulates glucose sensing and glucagon secretion in pancreatic alpha cells

The secretion of glucagon by pancreatic alpha cells is regulated by a number of external and intrinsic factors. While the electrophysiological processes linking a lowering of glucose concentrations to an increased glucagon release are well characterized, the evidence for the identity and function of...

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Detalles Bibliográficos
Autores principales: Moede, Tilo, Leibiger, Barbara, Vaca Sanchez, Pilar, Daré, Elisabetta, Köhler, Martin, Muhandiramlage, Thusitha P., Leibiger, Ingo B., Berggren, Per-Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678872/
https://www.ncbi.nlm.nih.gov/pubmed/33214580
http://dx.doi.org/10.1038/s41598-020-76863-z