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TARGETING TELOMERASE FOR CANCER THERAPY

Telomere maintenance via telomerase reactivation is a nearly universal hallmark of cancer cells which enables replicative immortality. In contrast, telomerase activity is silenced in most adult somatic cells. Thus, telomerase represents an attractive target for highly selective cancer therapeutics....

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Detalles Bibliográficos
Autores principales: Guterres, Adam N, Villanueva, Jessie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678952/
https://www.ncbi.nlm.nih.gov/pubmed/32733068
http://dx.doi.org/10.1038/s41388-020-01405-w