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TARGETING TELOMERASE FOR CANCER THERAPY
Telomere maintenance via telomerase reactivation is a nearly universal hallmark of cancer cells which enables replicative immortality. In contrast, telomerase activity is silenced in most adult somatic cells. Thus, telomerase represents an attractive target for highly selective cancer therapeutics....
Autores principales: | Guterres, Adam N, Villanueva, Jessie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678952/ https://www.ncbi.nlm.nih.gov/pubmed/32733068 http://dx.doi.org/10.1038/s41388-020-01405-w |
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