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PD-L1 expression in equine malignant melanoma and functional effects of PD-L1 blockade

Programmed death-1 (PD-1) is an immunoinhibitory receptor expressed on lymphocytes. Interaction of PD-1 with its ligand PD-ligand 1 (PD-L1) delivers inhibitory signals and impairs proliferation, cytokine production, and cytotoxicity of T cells. In our previous studies, we have developed anti-bovine...

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Detalles Bibliográficos
Autores principales: Ganbaatar, Otgontuya, Konnai, Satoru, Okagawa, Tomohiro, Nojima, Yutaro, Maekawa, Naoya, Minato, Erina, Kobayashi, Atsushi, Ando, Ryo, Sasaki, Nobuya, Miyakoshi, Daisuke, Ichii, Osamu, Kato, Yukinari, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678989/
https://www.ncbi.nlm.nih.gov/pubmed/33216754
http://dx.doi.org/10.1371/journal.pone.0234218