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HER2 splice variants in breast cancer: investigating their impact on diagnosis and treatment outcomes

Overexpression of the HER2 receptor occurs in approximately 20% of breast cancer patients. HER2 positivity is associated with poor prognosis and aggressive tumour phenotypes, which led to rapid progress in HER2 targeted therapeutics and diagnostic testing. Whilst these advances have greatly increase...

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Detalles Bibliográficos
Autores principales: Hart, Vic, Gautrey, Hannah, Kirby, John, Tyson-Capper, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679030/
https://www.ncbi.nlm.nih.gov/pubmed/33245725
http://dx.doi.org/10.18632/oncotarget.27789