Integration of single-cell datasets reveals novel transcriptomic signatures of β-cells in human type 2 diabetes

Pancreatic islet β-cell failure is key to the onset and progression of type 2 diabetes (T2D). The advent of single-cell RNA sequencing (scRNA-seq) has opened the possibility to determine transcriptional signatures specifically relevant for T2D at the β-cell level. Yet, applications of this technique...

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Detalles Bibliográficos
Autores principales: Bosi, Emanuele, Marselli, Lorella, De Luca, Carmela, Suleiman, Mara, Tesi, Marta, Ibberson, Mark, Eizirik, Decio L, Cnop, Miriam, Marchetti, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Standard Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679065/
https://www.ncbi.nlm.nih.gov/pubmed/33575641
http://dx.doi.org/10.1093/nargab/lqaa097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679065/
https://www.ncbi.nlm.nih.gov/pubmed/33575641
http://dx.doi.org/10.1093/nargab/lqaa097

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