Potency and timing of antiviral therapy as determinants of duration of SARS-CoV-2 shedding and intensity of inflammatory response

To affect the COVID-19 pandemic, lifesaving antiviral therapies must be identified. The number of clinical trials that can be performed is limited. We developed mathematical models to project multiple therapeutic approaches. Our models recapitulate off-treatment viral dynamics and predict a three-ph...

Descripción completa

Detalles Bibliográficos
Autores principales: Goyal, Ashish, Cardozo-Ojeda, E. Fabian, Schiffer, Joshua T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679107/
https://www.ncbi.nlm.nih.gov/pubmed/33097472
http://dx.doi.org/10.1126/sciadv.abc7112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679107/
https://www.ncbi.nlm.nih.gov/pubmed/33097472
http://dx.doi.org/10.1126/sciadv.abc7112

Ejemplares similares