Probing the ionotropic activity of glutamate GluD2 receptor in HEK cells with genetically-engineered photopharmacology

Glutamate delta (GluD) receptors belong to the ionotropic glutamate receptor family, yet they don’t bind glutamate and are considered orphan. Progress in defining the ion channel function of GluDs in neurons has been hindered by a lack of pharmacological tools. Here, we used a chemo-genetic approach...

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Detalles Bibliográficos
Autores principales: Lemoine, Damien, Mondoloni, Sarah, Tange, Jérome, Lambolez, Bertrand, Faure, Philippe, Taly, Antoine, Tricoire, Ludovic, Mourot, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679134/
https://www.ncbi.nlm.nih.gov/pubmed/33112237
http://dx.doi.org/10.7554/eLife.59026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679134/
https://www.ncbi.nlm.nih.gov/pubmed/33112237
http://dx.doi.org/10.7554/eLife.59026

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