Alpha-satellite RNA transcripts are repressed by centromere–nucleolus associations

Although originally thought to be silent chromosomal regions, centromeres are instead actively transcribed. However, the behavior and contributions of centromere-derived RNAs have remained unclear. Here, we used single-molecule fluorescence in-situ hybridization (smFISH) to detect alpha-satellite RN...

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Detalles Bibliográficos
Autores principales: Bury, Leah, Moodie, Brittania, Ly, Jimmy, McKay, Liliana S, Miga, Karen HH, Cheeseman, Iain M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679138/
https://www.ncbi.nlm.nih.gov/pubmed/33174837
http://dx.doi.org/10.7554/eLife.59770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679138/
https://www.ncbi.nlm.nih.gov/pubmed/33174837
http://dx.doi.org/10.7554/eLife.59770

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