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Alpha-satellite RNA transcripts are repressed by centromere–nucleolus associations
Although originally thought to be silent chromosomal regions, centromeres are instead actively transcribed. However, the behavior and contributions of centromere-derived RNAs have remained unclear. Here, we used single-molecule fluorescence in-situ hybridization (smFISH) to detect alpha-satellite RN...
Autores principales: | Bury, Leah, Moodie, Brittania, Ly, Jimmy, McKay, Liliana S, Miga, Karen HH, Cheeseman, Iain M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679138/ https://www.ncbi.nlm.nih.gov/pubmed/33174837 http://dx.doi.org/10.7554/eLife.59770 |
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