Cargando…

BDNF-induced local translation of GluA1 is regulated by HNRNP A2/B1

The AMPA receptor subunit GluA1 is essential for induction of synaptic plasticity. While various regulatory mechanisms of AMPA receptor expression have been identified, the underlying mechanisms of GluA1 protein synthesis are not fully understood. In neurons, axonal and dendritic mRNAs have been rep...

Descripción completa

Detalles Bibliográficos
Autores principales: Jung, Youngseob, Seo, Ji-Young, Ryu, Hye Guk, Kim, Do-Yeon, Lee, Kyung-Ha, Kim, Kyong-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679154/
https://www.ncbi.nlm.nih.gov/pubmed/33219033
http://dx.doi.org/10.1126/sciadv.abd2163