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Docking-based identification of small-molecule binding sites at protein-protein interfaces
Protein-protein interactions play an essential role in many biological processes, and their perturbation is a major cause of disease. The use of small molecules to modulate them is attracting increased attention, but protein interfaces generally do not have clear cavities for binding small compounds...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679229/ https://www.ncbi.nlm.nih.gov/pubmed/33250973 http://dx.doi.org/10.1016/j.csbj.2020.11.029 |