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LINC00460-miR-149-5p/miR-150-5p-Mutant p53 Feedback Loop Promotes Oxaliplatin Resistance in Colorectal Cancer

Oxaliplatin resistance is a major challenge in the clinical treatment for advanced colorectal cancer (CRC). Long non-coding RNAs (lncRNAs) are involved in tumorigenesis and progression as critical regulators, while their potential roles in chemoresistance are poorly understood. In this study, we rep...

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Detalles Bibliográficos
Autores principales: Meng, Xiangfeng, Sun, Wu, Yu, Jing, Zhou, Yu, Gu, Yuanyuan, Han, Jiayi, Zhou, Likun, Jiang, Xiaohong, Wang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679243/
https://www.ncbi.nlm.nih.gov/pubmed/33251049
http://dx.doi.org/10.1016/j.omtn.2020.10.018