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Improved Cancer Targeting by Multimerizing Aptamers on Nanoscaffolds

Aptamers are short single-stranded oligonucleotides selected to bind with high affinity and specificity to a target. In contrast to antibodies, aptamers can be produced in large-scale in vitro systems without the need for any biological agents, making them highly attractive as targeting ligands for...

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Detalles Bibliográficos
Autores principales: Omer, Marjan, Andersen, Veronica Liv, Nielsen, Jesper Sejrup, Wengel, Jesper, Kjems, Jørgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679244/
https://www.ncbi.nlm.nih.gov/pubmed/33251048
http://dx.doi.org/10.1016/j.omtn.2020.10.013