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Improved Cancer Targeting by Multimerizing Aptamers on Nanoscaffolds
Aptamers are short single-stranded oligonucleotides selected to bind with high affinity and specificity to a target. In contrast to antibodies, aptamers can be produced in large-scale in vitro systems without the need for any biological agents, making them highly attractive as targeting ligands for...
Autores principales: | Omer, Marjan, Andersen, Veronica Liv, Nielsen, Jesper Sejrup, Wengel, Jesper, Kjems, Jørgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679244/ https://www.ncbi.nlm.nih.gov/pubmed/33251048 http://dx.doi.org/10.1016/j.omtn.2020.10.013 |
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