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Towards better understanding of the influence of process parameters in roll compaction/dry granulation on throughput, ribbon microhardness and granule failure load

A key quality attribute for solid oral dosage forms is their hardness and ability to withstand breaking or grinding. If the product is to be manufactured continuously, it can be of interest to monitor the hardness of the material at different stages of manufacturing. Using the controlled process par...

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Detalles Bibliográficos
Autores principales: Wilms, Annika, Kleinebudde, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679258/
https://www.ncbi.nlm.nih.gov/pubmed/33251510
http://dx.doi.org/10.1016/j.ijpx.2020.100059