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APOL1 polymorphism modulates sphingolipid profile of human podocytes

Apolipoprotein L1 (APOL1) wild type (G0) plays a role in the metabolism of sphingolipids, glycosphingolipids, sphingomyelin and ceramide, which constitute bioactive components of the lipid rafts (DRM). We asked whether APOL1 variants (APOL1-Vs) G1 and G2 carry the potential to alter the metabolism o...

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Detalles Bibliográficos
Autores principales: Valsecchi, Manuela, Cazzetta, Valentina, Oriolo, Ferdinando, Lan, Xiqian, Piazza, Rocco, Saleem, Moin A., Singhal, Pravin C., Mavilio, Domenico, Mikulak, Joanna, Aureli, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679335/
https://www.ncbi.nlm.nih.gov/pubmed/32915357
http://dx.doi.org/10.1007/s10719-020-09944-w