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CB1 receptor antagonist rimonabant protects against chronic intermittent hypoxia-induced bone metabolism disorder and destruction in rats

OBJECTIVE: The endocannabinoid system (ECS) regulates bone turn-over and remodeling. Chronic intermittent hypoxia (CIH) occurring during obstructive sleep apnea (OSA) may lead to disorders of the ECS and bone metabolism abnormalities. This study aimed to investigate whether or not the cannabinoid re...

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Detalles Bibliográficos
Autores principales: Dou, Zhan-jun, Gao, Xiao-Ling, Jia, Yan-li, Chen, Jie, Yang, Jiao-Jiao, Chen, Yan, Wu, Shu-jie, Liu, Tao, Wang, Mei-ting, Yang, Chong, Zhang, Na, Wang, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679350/
https://www.ncbi.nlm.nih.gov/pubmed/31898189
http://dx.doi.org/10.1007/s11325-019-02009-9