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Assembling custom side chains on proteoglycans to interrogate their function in living cells

Proteoglycans (PGs) are composed of a core protein and one or more chains of glycosaminoglycans (GAGs). The highly heterogeneous GAG chains play an irreplaceable role in the functions of PGs. However, the lack of an approach to control the exact structure of GAG chains conjugated to PGs tremendously...

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Detalles Bibliográficos
Autores principales: Wang, Wenshuang, Han, Naihan, Xu, Yingying, Zhao, Yunxue, Shi, Liran, Filmus, Jorge, Li, Fuchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679400/
https://www.ncbi.nlm.nih.gov/pubmed/33219207
http://dx.doi.org/10.1038/s41467-020-19765-y