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Modular affinity-labeling of the cytosine demethylation base elements in DNA

5-methylcytosine is the most studied DNA epigenetic modification, having been linked to diverse biological processes and disease states. The elucidation of cytosine demethylation has drawn added attention the three additional intermediate modifications involved in that pathway—5-hydroxymethylcytosin...

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Detalles Bibliográficos
Autores principales: Wang, Fanny, Zahid, Osama K., Ghanty, Uday, Kohli, Rahul M., Hall, Adam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679407/
https://www.ncbi.nlm.nih.gov/pubmed/33219273
http://dx.doi.org/10.1038/s41598-020-76544-x