Cargando…
Modular affinity-labeling of the cytosine demethylation base elements in DNA
5-methylcytosine is the most studied DNA epigenetic modification, having been linked to diverse biological processes and disease states. The elucidation of cytosine demethylation has drawn added attention the three additional intermediate modifications involved in that pathway—5-hydroxymethylcytosin...
Autores principales: | Wang, Fanny, Zahid, Osama K., Ghanty, Uday, Kohli, Rahul M., Hall, Adam R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679407/ https://www.ncbi.nlm.nih.gov/pubmed/33219273 http://dx.doi.org/10.1038/s41598-020-76544-x |
Ejemplares similares
-
AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation
por: Nabel, Christopher S., et al.
Publicado: (2012) -
TET proteins and the control of cytosine demethylation in cancer
por: Scourzic, Laurianne, et al.
Publicado: (2015) -
Active demethylation in mouse zygotes involves cytosine deamination and base excision repair
por: Santos, Fátima, et al.
Publicado: (2013) -
APOBEC3A efficiently deaminates methylated, but not TET-oxidized, cytosine bases in DNA
por: Schutsky, Emily K., et al.
Publicado: (2017) -
Enzymatic approaches for profiling cytosine methylation and hydroxymethylation
por: Wang, Tong, et al.
Publicado: (2021)