Involvement of FATP2-mediated tubular lipid metabolic reprogramming in renal fibrogenesis

Following a chronic insult, renal tubular epithelial cells (TECs) contribute to the development of kidney fibrosis through dysregulated lipid metabolism that lead to lipid accumulation and lipotoxicity. Intracellular lipid metabolism is tightly controlled by fatty acids (FAs) uptake, oxidation, lipo...

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Detalles Bibliográficos
Autores principales: Chen, Yuting, Yan, Qi, Lv, Mengyue, Song, Kaixin, Dai, Yue, Huang, Yi, Zhang, Le, Zhang, Cuntai, Gao, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679409/
https://www.ncbi.nlm.nih.gov/pubmed/33219209
http://dx.doi.org/10.1038/s41419-020-03199-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7679409/
https://www.ncbi.nlm.nih.gov/pubmed/33219209
http://dx.doi.org/10.1038/s41419-020-03199-x

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